Noopept Review – The Secret to A Smarter You

Noopept is a powerful nootropic that is widely used to help boost brain function and improve memory. There have been several claims made about the effect noopept has on mood, memory, anxiety and cognitive function. The purpose of this Noopept review is to look into these claims, and also at its side-effects, how it can be stacked with other supplements, and how it fares when compared to a similar nootropic – Piracetam.

What is Noopept

Noopet, also known as n-phenylacetyl-l-prolylglycine ethyl ester or GVS-111, is a nootropic that is widely used for cognitive enhancement. Noopept was developed in Russia, where it was patented by the pharmaceutical company JSC LEKKO Pharmaceuticals, in 1996. It is sold a prescription drug in Russia, and in countries that were a part of the former Soviet Union. Noopept is also patented in the United States, but is sold as a supplement.

Noopept is an ampakine nootropic, so it works by binding to AMPA-type receptors in the brain. Ampakines boost the activity of a neurotransmitter called glutamate, which enhances memory and learning. Noopept works similarly to racetam compounds, such as Piracetam. The major difference between racetams and noopept is that noopept does not have a 2-oxo-pyrrolidine core. Noopept is far more potent when compared to other racetams and is usually preferred by nootropic enthusiasts.

Noopept reviews by experienced users point to the nootropic helping with cognition, memory, learning, mood stability, and perception. There have been numerous studies conducted on noopept, and they support the theory that noopept is not merely a placebo – it really has many benefits when it is taken in recommended amounts.

Noopept Benefits

Improves Mood

One reason people take noopept is because it can help improve their mood. Noopept can help reduce stress and anxiety, and there have been studies that help substantiate this claim.

One clinical trial used noopept in the treatment of patients who were suffering from mild emotional or cognitive troubles following strokes or brain injuries [1]. In order to treat their irritability and anxiety, the patients were given 10 mg of noopept twice a day. This treatment helped reduce anxiety and irritability in the patients, and the study also reported the added benefits of more emotional stability and better sleep.

Another study came to a similar conclusion about the effects of noopept. This study was conducted on rats who were injected with noopept, and then their brain waves were monitored [2]. It was observed that noopept increased both alpha and beta waves in the brain. Alpha brain waves are associated with relaxation, while Beta brain waves are associated with focus and cognition – therefore noopept helped improve focus, while keeping the subject in a relaxed state of mind.

Improves Memory and Cognitive Abilities

The primary reason people choose to use noopept is that it helps improve memory and cognition. Studies support this hypothesis, which has led to the popularity of this nootropic.

A study conducted on rats shows that noopept improved their learning rate after a single dose was administered [3]. This was not observed across the board, since some rats required more than a single dose to show considerable effects.

Another study, that was conducted on rats with learning and memory impairment, found that administering noopept helped them keep and recall memories [4].

Boosts Brain Health

There is considerable evidence supporting that noopept can help improve brain heath. Noopept acts as a neuroprotective compound – so it helps protect the neurons in your brain from damage.

In one of the studies conducted on noopept, it was found that it helps prevent cell death in the brain from amiloyd cytotoxicity, a major cause for Parkinson’s and Alzheimer’s [5].

Another study on the neuroprotective properties of noopept came to the same conclusion – that it helps prevent ionic disbalance, excitotoxicity, free radicals and other forms of brain damage that can be found in those with Alzheimer’s disease [6].

Noopept also boosts Nerve Growth Factor (NGF) and Brain Derived Neurotrophic Factor (BDNF) – two proteins that are important for neuroplasticity and the ability of the brain to learn and retain new things [7]. This study was conducted on rats, and it found that the long-term administration of noopept increased BDNF, which boosts cognitive function.

Noopept Dosage

As with all nootropics, the dosage of noopept varies from person to person. Typically, the dosage ranges between 10-30 mg per day. You may choose to take it all at once, but most users phase it out through the day by taking low doses twice or thrice.

First timers should start out with a very low dose, as low as 5 mg, to see how noopept affects them. There have been reports of users feeling powerful effects at 10 mg, while others have reported mild-to-moderate effects at higher doses. Noopept seems to have a ceiling with doses, where anything above 40 mg does not seem to have additional effects.

How Long Does Noopept Last

The effects of noopept can be felt within minutes of taking it, but it has a short half-life. This means that the drug will be out of your system in a few hours. The effects only last for 3 to 4 hours for most users, and then it wears off. Because it has a short half-life, most users take smaller doses throughout the day instead on a single large dose. The most common dosage taken by beginners is 10 mg, once in the morning on an empty stomach, to help get the most out of noopept. Some may need to take several 10 mg doses through the day for the effects of noopept to last longer.

My Noopept Experience

My Background

Nootropics is one topic I spend a lot of time researching. I am usually very curious about the benefits nootropics can have on your mind and body. Even though I am open to experimenting with nootropics I am not familiar with, I approach them with caution and conduct the necessary research. I decided to try noopept because I was struggling with my work. My focus and memory were not what they used to be, and I wanted to try a nootropic that will help boost my brain.

My noopept review is based on using it for a few weeks – therefore I cannot comment on its long-term effects.


I got my hands on 20 mg noopept capsules. It seemed like a huge dose, so I decided to only take half of it. To get the best effects, I took it on an empty stomach. After experimenting with noopept for a week, I take 10 mg of it in the morning and 10 mg during lunchtime. I have found that taking noopept alongside food rich in choline (eggs, fish and dairy) helps boost its effects.


Taking a single dose in the morning improved my awareness and focus, but its effects wore off a few hours later, and I felt tired and cranky. After I decided to go for two doses, things improved. I feel more focused when I’m working. My mind used to wander while I was trying to complete a task, but after taking noopept, that’s happening less and less. I have been feeling more confident lately; I guess because I am less compelled by anxiety over my productivity.

Noopept And Alcohol

Since noopept increases mental awareness, many people take it alongside alcohol. Noopept is a stimulant, while alcohol is a depressant, therefore, it makes sense that taking noopept will reduce the effect alcohol has. Most people do claim that taking noopept with alcohol allows them to function normally, but combining the two is not a good idea.

Because you don’t feel drunk if you take noopept with alcohol, it is very easy to cross your alcohol limit and too much alcohol in your blood is a terrible idea. Combining the two can also cause side effects such as headaches, gastrointestinal issues, fatigue, insomnia and problems with short-term memory.

Noopept Side Effects

Noopept is generally considered as safe if the recommended doses are taken. But, like with every drug, side-effects are a possibility. High doses can cause the following side-effects :

  • Fatigue
  • Headaches
  • Sleep disturbances
  • Irritability
  • Gastrointestinal issues
  • Increased blood pressure

Noopept Vs Piracetam

In nootropic circles, noopept is often compared to piracetam. As nootropics, their structures are comparable and their effects are considerably similar as well. They seem to be more alike than different, but there are some key differences between these two popular nootropics:


Bioavailability of a nootropic is its ability to be absorbed and used by the body. Piracetam seems to have better bioavailability than noopept, and its effects last longer. But despite better bioavailability, piracetam is nowhere as powerful as noopept.


The recommended dosage of noopept is 10 to 30 mg, and it should be spaced out through the day to get the maximum benefits from it. Those who want to take 30 mg of noopept should take 10 mg thrice a day.

Piracetam, on the other hand, requires a much larger dose. The recommended dose is between 1,600 mg to 4,800 mg a day, although experienced users can take an even higher dose.

How to Use

Even though noopept is soluble in water, the recommended method of taking it is sublingually (placing it under your tongue and allowing your saliva to dissolve it). With piracetam, you can take it orally with water or water-based drinks.

Noopept and piracetam can also be stacked to give users a better experience with cognitive enhancement.

Noopept Stacks

Noopept is a potent nootropic, but you can always boost its powers by stacking it with other nootropics or supplements. It is important to know what you’re looking to get out of noopept before choosing a noopept stack. Here are some ways you can stack noopept to make your nootropic experience even better:

Focus Boost with Choline

In order to improve your memory and focus, you can choose to stack noopept with choline. Choline is an essential macronutrient that we need, and noopept helps in improving the brain’s sensitivity to it. This stack helps in enhancing the effects of both noopept and choline, and is popular among noopept users.

Improved Memory and Cognition with Piracetam and Alpha GPC

One reason to use noopept is the cognitive enhancement it provides. In order to improve upon this, you can stack noopept with Piracetam and Alpha GPC. Noopept and piracetam are two rather similar nootropics – they both help with memory and cognition. Alpha GPC is a choline supplement that helps improve the effect of them both. Those looking for a cognitive boost, and better memory, will benefit from this stack.

Better Mood with Aniracetam and Sulbutiamine

Aniracetam is a nootropic that helps enhance creativity and motivation, while Sulbutiamine is a form of vitamin B1 that is used in the treatment of weakness or fatigue. Stacking them both with noopept will help reduce anxiety and elevate mood. This stack is popular among those who want the cognitive boost of noopept and also want to enhance their mood and creativity.

Noopept For Sale

To get the benefits of noopept, you need to procure it from a legit source that you can trust. Since noopept is not an ordinary supplement, you cannot get a hold of it at most health stores. The best way to get your hands on noopept is to look for it online, and I recommend the following sites:


HRSupplements sells noopept in the form of a powder and capsules. They offer discounts if you buy in bulk from them. They also offer free shipping throughout the United States as long as your order exceeds $39. Shipping to other countries is also an option, although you may have to pay extra.

Pure Nootropics

Pure Nootropics offers three forms of noopept – powder, capsules, and a sublingual solution. Their products are tested for purity and quality, and they offer a 30-day money-back guarantee if you’re not satisfied with the product. Shipping is free if you are located in the United States.


Noopept is widely used for its many benefits and minimal side effects. There is a lot of evidence that points to its safety when it is taken in the recommended doses. It helps improve memory, focus, and attention, and can also help elevate your mood and relieve you of anxiety.

Despite its safety and the many benefits it provides, it is important that you make an informed decision about taking noopept, especially if you’re new to nootropics. I hope this noopept review can help you decide if you’re interested in taking this powerful nootropic.

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